#NOVA #IVF #FENTILITY PRESS RELEASE NOVA IVF Fertility is witnessing a substantial increase in footfall of patients suffering from infertility from Tier Il and Ill cities in Tamil Nadu Chennai, India October 31", 2019: Infertility can be caused by a variety of diseases and medical conditionsand affects about one in six men and women of reproductive age. The causes for infertility are numerous but can be categorized around issues pertaining to ovulation and egg quality; sperm production, transport and function; fertilization; and implantation. NOVA IVF Fertility, one ofIndia's largest fertility service providers, has reported to have witnessed a rise in cases of infertility in Tier II and IlIl cities in Tamil Nadu. Previously, couples who were over 35 years of age were considered to have reduced reproductive potential and were advised IVF with donorgametes. Today, couples from rural areas have been found to have a lower potential to produce their own biological gametes than the couples from urban areas and were advised IVF cycles.When the ovarian reserve was highly reduced (low AMH, low AFC) and very poor quality of oocytes or poor sperm morphology and extremely low sperm quantity, they were advised on the third party reproduction using donor gametes, Nowadays, there seems to be an increasingnumber of young people even around 30 yrs onwards to have poor quantity and quality of eggs and sperms and hence, poor quality embryos.This trend is more obvious in rural areas than in urban areas..
Poor ovarian reserve (POR) is an important limiting factor for the success of any treatment modality for infertility.It indicates a reduction in quantity with or without quality of oocytes in women of reproductive age group.As a woman ages, the eggs and the cells around them can accumulate damage that is beyond repair, and such damages are commonly caused by contemporary lifestyle choices and habits.Factors such as use of pesticides in fruits and vegetables, passive smoking and consumption of unhygienic fast food, which is more common in rural areas is assumed to deplete the quality of eggs prematurely in women.With the increasing age, the body can also be affected by poor dietary intake, poor blood circulation, disturbed hormonal balance, autoimmune disorders, and other health problems too.
Addressing the concerns around diminishing ovarian reserve and the available treatment options, Dr Madhupriya, Fertility Consultant, NOVA IVI Fertility, Chennai commented, "We have been witnessing a substantial rise in cases of infertility by in Tier Il and III cities in Tamil Nadu, the 8most common increasing concern being low quality sperm/eggs. The couples who come for fertility treatments may have fair knowledge about IVF only and in some cases, many would have had failed IVF cvcles which made them believe that they can never conceive again. However,alongside IVF, there are several fertility treatments which can lead to obtaining their own biological gametes. The couple can go ahead with donor gametes if at all this cycle fails. It is important that patients are counselled, basis their existing medical conditions along with information aboutthe various treatment options available.
"Diagnosis of Diminished Ovarian Reserve
AMH test is used to check whether one's ovarian reserve is appropriate for the age, assess the outcome of an IVF cycle as low levels of AMH could indicate a potentially poor response to IVF, know whether chemotherapy or ovarian surgery has affected fertility, diagnose an ovarian tumour or to plan pregnancy in future.A typical AMH level for a fertile woman is around 4.0 ng/ml;under 1.0 ng/ml is considered low and indicative of a diminished ovarian reserve.
a) Intra-Uiterine lnsemination (IUI )
IUI is a tertlilty treatment where sperm is inserted directly into a woman's uterus during ovalation; decreasing the journey for the sperm to the egg. During ovulation, the woman produces one egg that a picked up by the end of the fallopian tube where it waits to meet the sperm. An IUI deposits hgher concentrations of good quality sperm close to where the egg is waiting which increases the chances that the egg and sperm will unite.
b) Intra-Cytoplasmic Speem tnjection (ICSI)
intracytoplasmic sperm injection is an in- vitro fertilization (IVF) procedure in which a single sperin cell is injected directly into the cytoplasm of an egg.This technique is used in order to prepare the gametes for obtaining the embryos that may be transferred to a maternal uterus.
Case study 1:
Growth Hormone Protocol
Shallaja (name changed), aged 30 years, came to NOVA IVF Fertility, Chennal for diagnosis and treatment.The patient had a history of many failed IUI cycles, 1 failed ICSI cycle also a history of severe endometriosis with a tubal disease, for which her tubes were disconnected prior to the first cycle of iVs When she visited Nova IVF Fertility a year after the failed cycle, her AMH level was then 0.6ng/ml and hence
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